In this study we describe a case with interface fluid syndrome developing after laser in situ keratomileusis (LASIK) result from steroid-induced intraocular pressure (IOP) elevation.The aim of this study was to emphasize the importance of ocular manifestations and clinical course of interface fluid syndrome which leads to inaccurately low central applanation tonometry measurements that obscure the diagnosis of steroid-induced glaucoma. Early recognition and treatment of this syndrome are essential to avoid complications associated with prolonged elevated IOP.