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Automated Perimetry
Carbonic Anhydrase Inhibitors
Intra Ocular Lens Power Calculation and Optic Biometry...
Visual Field Defects in Glaucoma
Visual Field Defect and Retinal Nerve Fiber Layer Defect in a Case of Optic Nerve Head Drusen...
Current Minimal Invasive Angle Procedures Without Implants for the Treatment of Glaucoma...
Intra Ocular Lens Power Calculation and Optic Biometry...
Automated Perimetry
Carbonic Anhydrase Inhibitors
Visual Field Defect and Retinal Nerve Fiber Layer Defect in a Case of Optic Nerve Head Drusen...
Glokom-Katarakt 2020 , Vol 15 , Num 3
Abstract Free Full Text Similar Articles Mail to Author
Correlation Between Retinal Nerve Fiber Layer, Optic Nerve Head and Macular Parameters and Structure Function Relationship in Glaucoma
Tugba AYDOGAN GEZGINASLAN1, Betul Ilkay SEZGIN AKCAY2, Esra KARDES2
1MD., Bulancak State Hospital, Eye Clinic, Giresun, Turkey
2MD., Associate Prof., Umraniye Education and Research Hospital, Eye Clinic, Istanbul, Turkey
DOI : 10.37844/glauc.cat.2020.15.32 Purpose: To evaluate correlation between visual fi eld indices and spectral domain optical coherence tomography (SD-OCT) parameters and correlation among SD-OCT parameters to have a better understanding of role of SD-OCT parameters in clinical practice.

Materials and Methods: This is a retrospective controlled clinical study. Three hundred forty-three eyes (91 healthy, 80 ocular hypertension, 97 preperimetric glaucoma and 75 early glaucoma eyes) were analyzed. Retinal nerve fi ber layer (RNFL), macular, optic nerve head (ONH) parameters were measured with SD-OCT. Correlation between visual fi eld indices and SD-OCT parameters and correlation among SD-OCT parameters were calculated.

Results: Average RNFL showed the best correlation with both mean deviation (MD) (r = 0.624) and pattern standard deviation (PSD) (r = 0.614). Other RNFL parameters, ganglion cell complex (GCC) parameters and total retina (TR) parameters showed moderate correlation whereas outer retina (OR) and ONH parameters showed poor correlation with MD. Correlation between RNFL and GCC parameters was strong. Correlation between RNFL and TR parameters was moderate. Poor correlation were found between OR parameters and both RNFL and GCC parameters. Moderate correlation was found between average RNFL and both rim area and rim volume. Other correlations with ONH parameters were poor.

Conclusion: Good structure function relationship is present between visual fi eld indices and SD-OCT parameters like RNFL and GCC parameters. These parameters refl ect the severity of glaucoma and can be used for glaucoma monitoring. TR and some ONH parameters like rim area and volume can give supplementary information to use in clinical practice. Keywords : Ganglion cell complex, Optic nerve head; retinal nerve fi ber layer, Spectral domain optical coherence tomography, Structure function relationship

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